Genetics+Pedigrees

Genetics of Blue People
The actual genetics of Blue People is not very complicated.

1. The families involved lived in small, close knit, isolated communities. Why is this both a help and a hindrance to studying their genetics?

2. Through the various links below, you will find several different pedigrees purporting to be the "real" pedigree of the blue people. Why are the pedigrees different?

3. Which of the pedigrees is most likely the correct one? Support your answer.

4. What is the probability that any child of Daniel and Laura Stacy will be blue?

How Is This Disorder Inherited?
The following links, and their sub-links will help you answer the questions above and the pedigree assignment below. [|http://www.people.virginia.edu/%7Erjh9u/fugped1.html|http://www.people.virginia.edu/~rjh9u/fugped1.html]

[|http://www.people.virginia.edu/%7Erjh9u/diaenzfreq.html|http://www.people.virginia.edu/~rjh9u/diaenzfreq.html]

[|http://www.people.virginia.edu/%7Erjh9u/bluemend.html|http://www.people.virginia.edu/~rjh9u/bluemend.html]

How to Make Pedigrees [|http://www.people.virginia.edu/%7Erjh9u/pedsymb.html|http://www.people.virginia.edu/~rjh9u/pedsymb.html]

Make Your Own Pedigree
Use the link above to draw the following pedigree with appropriate genotypes.

Benjy Stacy (blue) marries Emily Cole. They have five children Abigail, Beth, Caleb, Erin (blue). Benjy's parents are both normal. Benjy's sister Anna is normal, but her two sons are blue.

Emily's mother Fran is blue, but her father George is not. Emily's brother is normal.

Abigail Stacy marries Kevin, a normal man. They have three normal boys and one blue girl.

Daniel Stacy marries Laura, a blue woman. Their children Hannah, Issac, and Jessica are normal.